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Mar. 7th, 2022 12:24 pm
selenak: (Sternennacht - Lefaym)
[personal profile] selenak
This weekend I had two antivaxxers trying to enlist/convert me, one of whom was also a Putin defender going on abouto how the "mainstream media" was reporting it all wrong. But at least I'm related to neither of them; a friend of mine has to put up with his own daughter insisting that covid does not exist. Meanwhile, I, alas, had it (with symptoms) last month, despite having been vaccinated because of the new Ommicron variant, and I can tell you, fun this was not. Have some Ukraine related links:

Ukrainian demonstrations in Russia-occupied Kherson

Article about Natalya Sindeya, the founder of Dozhd, one of the last independent Russian media which was just shut down.

Profile of Volodymyr Zelensky, one of several to be published in the last ten days; this one in the New Yorker

Date: 2022-03-07 12:07 pm (UTC)
elisi: sunflower field (Sunflowers)
From: [personal profile] elisi
Sorry to hear you caught covid! We all caught it last summer - Delta - despite being vaccinated. Dread to think what it'd have been like if we'd not had the vaccine.

And thank you for the links, I'd not seen the New Yorker piece before.

Date: 2022-03-07 12:24 pm (UTC)
liriaen: person in white kimono drawing katana (Default)
From: [personal profile] liriaen
Thank you for the New Yorker link; hadn't seen this.

I hope your Covid doesn't outstay its initial visit; I have a vague feeling that my current bouts of fatigue and flash exhaustions are bit of a long tail. *shrugs* It could be worse, though, so: small mercies, in the light of general fear and insanity. Hold on tight!

Date: 2022-03-07 01:29 pm (UTC)
trobadora: (Default)
From: [personal profile] trobadora
So sorry you caught covid! I hope you're feeling better and aren't having any long-term effects.

a friend of mine has to put up with his own daughter insisting that covid does not exist

Ugh, that is the worst, when someone you care about falls down that rabbit hole. :(

Date: 2022-03-07 08:38 pm (UTC)
trobadora: (Default)
From: [personal profile] trobadora
*hugs*

Here's hoping at least the cold will get better quickly.

Date: 2022-03-07 01:44 pm (UTC)
ratcreature: Like a spork between the eyes. (spork)
From: [personal profile] ratcreature
Sorry to hear you got sick, and fingers crossed you won't get hit with any nasty longterm effects

This trend to deny reality that you don't like is maddening. And wtf even is this "mainstream media" argument? By now everyone who hasn't lost somebody to covid at least knows somebody else who has lost somebody close to them, and it's obviously more death and illness than in pre-covid times. And right now in my city there are Ukrainian refugees sheltering in our central exhibition hall, because they fled being bombed. Do they think somebody hired over a million "crisis actors" as fake refugees?? I know that there's some bizarre disinformation campaign that claims Ukrainians are blowing up their own cities or some nonsense, but this is just ridiculous.

I mean, I wish we had managed to create a different, more stable and ideally nuke-free security architecture in the 90s when maybe there had been a chance for it as much as the next person who does not want to be in our crapsack timeline, but clearly in the "pick your protector umbrella" reality we go stuck with, any Eastern European country that successfully managed to push to get in NATO had very good reason to do so, as events now show, so these "it's all NATO's fault" Putin apologists who thinks some people just need to be resigned to be an imperial sphere of interest without their say-so, should dare to tell that to anybody from say the Baltics to their face.

Date: 2022-03-07 02:48 pm (UTC)
ratcreature: Like a spork between the eyes. (spork)
From: [personal profile] ratcreature
Urgh. I've encountered some level of conspiratorial thinking in RL, like the "Ukrainian revolution was a CIA plot" kind of thing, and some of the "Ukrainian nationalists are all Nazis" takes, but not this extreme and it was all before Putin actually attacked Ukraine. I really hope they STFU about that now.

TBH I don't know how disproportionate the influence of right wing extremists in Ukrainian military or militias might be compared to their tiny electoral success (I mean clearly extremists can leverage their influence, even with smallish percentages, as can be seen all over the EU) but from the outside Ukraine doesn't seem to have a larger Nazi problem than, say, France with its multiplying right wing extremist blocks. Or you know, Germany. And even if it was a significant problem, clearly Putin has no issues with that ideological bent, with that disturbing philosopher he's a fan of, Ilyin? Or being previously cozy with occasional Horthy fanboy Orban. Who incidentally doesn't get bombed or invaded for aggravating the US and the EU. Or for harassing gay people. (Apparently the Russian Orthodox church now says Ukraine has to be bombed to fend of the gays or something?? And yet, NATO members in reality much less pro-gay...)

Date: 2022-03-07 04:15 pm (UTC)
ratcreature: Like a spork between the eyes. (spork)
From: [personal profile] ratcreature
It really makes you wonder whether these people have ever talked to anybody from there who wasn't some disinformation Twitter or Facebook bot.

You know, I've been in a Russian language course for a few years now. I just for fun, but many are learning for family because they married a Russian speaker or are enganged and want to raise their children bilingual, talk with in-laws etc. And that includes some with family from Ukraine, but Russian speakers obviously, this being a Russian course, not Ukrainian.

So through that I have met somebody with in-laws in Eastern Ukraine, and over the years (all post-2014) they mentioned them every now and then, and they were actually "pro-Russian" in that they would have rather liked to keep close integration and open-borders with Russia, not the EU, if it was binary. They were close to the separatist area but not quite in it, but a bit to the North. It was impacted, but my classmate could still visit and she went there for their honeymoon when she eventually married her Ukrainian boyfriend and it was all "normal" despite the war nearby. As of last week her in-laws were now hiding and their area being bombed by the Russian army. They hadn't wanted to come to Germany when their family here tried to convince them that Russia planned to invade and they should get out "just in case" (though my classmate and ger husband didn't really believe it would be *this* bad either). They didn't believe anything bad would happen to them, are older and didn't want to abandon their place etc.

Our teacher (a Russian from St. Petersburg) has a cousin living in Kyiv, as of last week hiding in some bomb shelter with his young family, while the teacher's (anti-war, all internet savy) friends in St. Petersburg are now fearing arrest, and his parents (currently living in Moscow) fear for their savings...

Our course last week was half taken up by just catching up with what horrible new reality people are suddenly finding themselves in now.

Date: 2022-03-08 07:21 am (UTC)
beatrice_otter: Me in red--face not shown (Default)
From: [personal profile] beatrice_otter
By now everyone who hasn't lost somebody to covid at least knows somebody else who has lost somebody close to them


Uh, no. While I know a lot of people who have gotten covid (some of whom were extremely sick), I don't know anyone who has died of it, and if any of my friends or close acquaintances has lost someone due to covid, they haven't mentioned it to me. We're a rural area with just enough sensible people that things haven't gotten as bad as elsewhere. People in the community have died of covid, but nobody I was connected to even at second hand. Now, I don't need to have someone I know die of it to know it's real and masks are good and so is vaccination. But if I didn't believe the media or the CDC or anyone else, my personal lived experience would not be enough to convince me that covid was especially dangerous. (Thank God.)

Date: 2022-03-07 02:31 pm (UTC)
reverancepavane: (Default)
From: [personal profile] reverancepavane
...despite having been vaccinated...

Serum (blood) vaccines generally won't stop you becoming infected with any disease that primarily colonises the upper respiratory tract (which is why it was never considered economical to create a vaccine for the common cold), but they will definitely help stop the disease from colonising deeper into the body and help prevent both the serious and long term effects from catching it. [And speed the reduction in your viral load once it does trigger.] But as with all vaccines, your response depends on the strength of your own immune system, so if you are old or immunocompromised you may still need hospitalisation despite being vaccinated (although you probably won't need intensive care).

It basically has to do with the different mechanisms by which the secondary immune system is triggered in each part of the body. [While many immunologists mentioned this fact it was generally ignored by the politicians who wanted the problem gone, and seized upon by the anti-vaxxers (although they themselves naturally didn't actually understand what they were talking about).]

Date: 2022-03-08 06:49 am (UTC)
cahn: (Default)
From: [personal profile] cahn
Oh, I didn't know this! I mean, I knew the specifics about the covid-19 vaccine, that it didn't always stop breakthrough omicron infections but that it protected a great deal against serious and long-term effects, but I didn't know it was a general upper respiratory disease thing related to immune system mechanisms. That's fascinating! (Do you happen to have a cite where I can read more about the underpinnings of this? If not that's fine, I'm just kind of interested now :) )

Date: 2022-03-08 08:59 am (UTC)
reverancepavane: (Default)
From: [personal profile] reverancepavane
The different response is essentially that different antibodies (immunoglobulin [Ig]) are present in the blood (and associated tissues) and the mucus (and associated tissues). In the mucus membrane the primary antibody is IgA, whilst in the blood it is generally IgG.

IgA is a poor activator of the secondary immune system (the lymphocytes that do the majority of work in destroying the invader) anyway, and the cells that produce it does not get good exposure to blood-based vaccine, which means that they are not particularly sensitised to the attacker. They will still respond, but they are not as effective at it.

IgG and the cells that secrete naturally do get a good exposure to the vaccine, so the body produces many of them specifically designed to identify and attack the virus as a result of being vaccinated. This is important since in the process of doing this they signal the body to start producing the lymphocytes that actually attack the invader. [And, as an added bonus once you have had the disease or the vaccine the secondary immune system remembers the most effective type of cells to use to attack the virus and doesn't have to discover how through trial and error.]

When the coronavirus starts colonising the upper respiratory tract (particularly the nasopharynx region), it primarily encounters IgA. It is only when it essentially moves deeper into the body that it encounters IgG which then triggers the full immune response, before it can effectively colonise the lungs and enter the blood (both of which are where it causes serious health problems).

Note that once the secondary response fully awakens it attacks the virus both in the body and in the upper respiratory tract. Which is why you may start out with the same viral load when infected, but you reduce that load a lot quicker than an unvaccinated person (and thus get better sooner). [As well has having less risk of complications.]

The omicron strain has several mutations from the base strain that make it particularly good at initially colonising the upper respiratory tract. Which is why it is spreading a lot easier - an R of between 4-7 with a mean of about 5.5 has been reported (amongst a theoretical unvaccinated population, which is why the variation in results). [The original strain had an R of about 2.7.]

There are currently trials being undertaken with a nasal spray vaccine to sensitise the IgA, to get a better immediate immune response. However it is likely that these will only be available to front line medical personnel and those that can afford them, as they probably will have an effectiveness of only 3-6 months and the standard vaccines should protect against the serious side-effects of catching COVID. [We are seeing an effective six-fold reduction in the need for hospitalisation amongst those who are vaccinated.]

This is all highly simplified. Key words for more information are immunoglobin (IgA and IgG), complementary activation, lymphocytes (T-cells and B-cells), primary and secondary immune response, and memory cells.

Hope this helps.

Edited Date: 2022-03-08 09:04 am (UTC)

Date: 2022-03-09 06:40 am (UTC)
cahn: (Default)
From: [personal profile] cahn
Yes it does, thank you! I knew some of this, but not about the IgA vs. IgG, but your explanation makes a lot of sense and I'll have to read more about that. Thanks again!

Date: 2022-03-07 02:37 pm (UTC)
likeadeuce: (Default)
From: [personal profile] likeadeuce
Thank you for the links. I'm so sorry you were ill and I hope you make a full recovery but I can see how it's hard to sort out illness from everything else that's making it hard to rest well these days.

Date: 2022-03-07 05:35 pm (UTC)
tree_and_leaf: Watercolour of barn owl perched on post. (Default)
From: [personal profile] tree_and_leaf
Sorry you've been unwell, and wishing you a good recovery. Take it easy - it does often have a long tail...

Date: 2022-03-07 06:14 pm (UTC)
davetheanalyzer: (Default)
From: [personal profile] davetheanalyzer
Hope you're doing well. If possible, maybe limit news consumption to an hour a day. I heard that advice from author NK Jemisin and I found it helped improve my mental health a lot.

It can be frustrating trying to find reliable news on Ukraine from the lefty outlets. I can find it hard to tell if they focus on the U.S. potentially contributing or causing problems because U.S. citizens have more theoretical power to stop their government or they fall into the "If U.S. bad, rival/enemy country good" trap, failing to realize that multiple countries can suck in varying and different degrees simultaneously.

Date: 2022-03-08 06:41 pm (UTC)
davetheanalyzer: (Default)
From: [personal profile] davetheanalyzer
It's alright. I understand managing news intake mightn't be always be possible for certain reasons. If you can, make time for distraction and breaks from negative news (If you already know this advice, sorry if it's annoying).

Fortunately, the lefty news source I watch is actually bringing on Russian and Ukrainian people to interview to give their perspective. They started doing it somewhat before for Russia and a few others but I like this change. Some of the guests might disagree a bit about details or what to do but it's much more informative about what's going on in those two countries (Now I wish this news source does more for countries like North and South Korea, Cuba, Taiwan, etc.).

Date: 2022-03-08 06:44 am (UTC)
cahn: (Default)
From: [personal profile] cahn
Oh ugh, I'm sorry to hear that, both about the antivaxxers (which sounds rather distressing) and the covid, which sounds just vastly unpleasant. :( <3 (I remember you were ill but hadn't realized it was covid.) It sounds like a lot of people have lingering effects for a while -- take care of yourself <3

Re your third link: ngl, one of the reasons I wanted to read the Zweig was that Zelensky made me want to read about people who got thrust into impossible situations and were heroic in response, which I remembered you'd said about Marie Antoinette. (I mean, obviously very different situations and responses, of course!)

Date: 2022-03-12 01:26 am (UTC)
jesuswasbatman: (Default)
From: [personal profile] jesuswasbatman
Sorry to hear you got covid, and glad you're better now. As I probably told you my Bavarian boss caught it very early on during a trip home, and his very nasty symptoms ensured that I took it seriously.

Date: 2022-03-13 04:24 am (UTC)
bobbiewickham: Kalinda Sharma of The Good Wife (Default)
From: [personal profile] bobbiewickham
Sorry to hear you caught COVID; hopefully it is gone and you are recovered.

It doesn't surprise me that the anti-vaxxer was also a Putin apologist. Once you decide you can pick your own reality because you don't like the liberal bias of this one, why stop at just one issue?

Thanks for the links. I'm trying to thread the needle between staying informed and doomscrolling on Ukraine.

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